Dartmouth researchers studying new pancreatic cancer treatment
The researchers used CT scans with contrast enhancement to measure treatment response to pancreatic cancer photodynamic therapy.
The research team at Dartmouth set out to reduce the imaging obstacles presented by the treatment. The patients who were selected for the trial had inoperable pancreatic cancer.
According to the Norris Cotton Cancer Center, “Photodynamic therapy is a minimally invasive and nontoxic method of treating cancer with a drug, which, when activated by light, kills cancer cells. Cancer cells are identified using a drug called a photosensitizer. Other cells release the photosensitizer, but cancer cells hang onto the drug. When exposed to light, the cells containing the drug die. Since the response is chemically, not heat, induced, there is no damage to connective tissue.”
The clinical trials in London are now stepping up to phase two in which it will be attempted to destroy not just cancer cells, but whole tumors. Phase three of the study would likely expand its locations to include Boston or Dartmouth-Hitchcock Medical Center, Pogue said.
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