GIANTS (2-3) at PATRIOTS (5-0)

Line: NE by 16½.

Cote’s pick: NE 38-6.

TV: 8:20 p.m. , Fox/NFL Network

New England has won 18 straight home games, and the Biggies arrive with no running game and a bad defense. Oh, and be warned Daniel Jones: Bill Belichick as Pats lord is 19-5 vs. rookie quarterbacks — including 12-0 in Foxborough. Patriots losing Thursday would be by far the biggest shock of the season, and anything even resembling a competitive game would surprise.