MLB: Boston Red Sox at Baltimore Orioles

Boston starter Eduardo Rodríguez delivers a pitch during the first inning against the Orioles on Thursday afternoon in Baltimore.

The Boston Red Sox scored five runs from the fifth inning on to beat the host Baltimore Orioles 7-3 and spoil opening day at Camden Yards on Thursday.

The Orioles led 3-2 going into the sixth but Boston took the lead back in the top of the inning and did not look back for the fourth win in a row.

Baltimore starter Matt Harvey (0-1) threw 25 pitches in a rough first inning which could have been worse than the two runs he surrendered. Harvey moved on from that and gave the Orioles a strong start, charged with four earned runs on seven hits in five-plus innings. Harvey struck out five.

Boston lefty Eduardo Rodriguez (1-0) got off to a similar start as he gave up a two-run homer in the first inning as well. Rodriguez was making his first start in 557 days after missing last season with COVID-19 then myocarditis. He started the season on the 10-day injured list as he had been dealing with left elbow inflammation dating to the end of spring training.

As was the case with Harvey, Rodriguez settled in and gave the Red Sox five innings, allowing three earned runs on four hits with seven strikeouts.

The Red Sox got this game going in a hurry.

After Harvey got the first out of the game, Alex Verdugo doubled. With two outs, Rafael Devers (2-for-3) hit a 1-1 offering about a dozen rows into the left-centerfield seats.

Baltimore answered in the bottom of the inning with Cedric Mullins leading off with a single and coming home on a two-out homer to right from Ryan Mountcastle.

Rodriguez stranded a pair of runners when he struck out Freddy Galvis to get out of the jam.

Pedro Severino homered to right with one down in the fourth to give Baltimore a 3-2 lead.

Harvey was pulled in the sixth after Devers and Christian Vazquez (3-for-5, run) led off with singles.

Boston ended up scoring twice in the inning — one off a groundout by Arroyo and another off a Franchy Cordero single — to take the lead.

The Red Sox added two runs in the seventh and another in the eighth off a home run from Kike Hernandez.

Baltimore was without manager Brandon Hyde after he was ejected by home plate umpire Jeremie Rehak for arguing that Rio Ruiz was struck in the arm by a pitch from Rodriguez. Bench coach Fredi Gonzalez took over for Hyde.

Recommended for you